Treatment Patterns, Healthcare Resource Utilization, and Costs Associated With Use of Atypical Antipsychotics as First vs Subsequent Adjunctive Treatment in Major Depressive Disorder

Major depressive disorder (MDD) can be associated with substantial emotional, social, and economic burdens. Delaying appropriate treatment may contribute to negative outcomes and increased healthcare use. This quick guide highlights real-world data on the use of atypical antipsychotics as adjunctive therapy, with a focus on treatment patterns and healthcare resource impact in patients with MDD. These insights may help providers consider how treatment sequencing decisions could influence both patient care and system-level outcomes.